Padrinos on Baptisms

Hello Nuestros Ranchos Forum,

I'm lookin at my ancestor Catarina de Mendoza baptism

https://familysearch.org/ark:/61903/3:1:S3HY-68J3-HHZ

and it says her padrino was Thomas de Villalobos who is her grandfather and
I was wondering if most padrinos are grandparents and relatives or can they
be anyone

Danny C. Alonso