Possible clues as to parents of Isabel Hurtado de Mendoza

Mr. Ricci there is a Hurtado de Mendoza on wikipedia married to a De Luna
and his father Diego Hurtado de Medoza was also married to a De Luna.

https://en.wikipedia.org/wiki/%C3%8D%C3%B1igo_L%C3%B3pez_de_Mendoza_y_Luna,_2nd_Duke_of_the_Infantado

Danny C. Alonso