Early Bobadilla Family from Colotlan

Does anyone know if there is a connection with the early Bobadilla Family from Colotlan and early Bobadilla Family from Tlaltenango.

Specifically, Antonio de Bobadilla (abt 1670) and Maria de Avila (abt 1675).
Their children:
Margarita de Bobadilla b: ABT 1690 Bolaños, Jalisco, Mexico
Joseph Andres de Bobadilla b: ABT 1693
Juan Pedro de Bobadilla b: ABT 1695
Nicolas de Bobadilla b: ABT 1697
Gertrudis de Bobadilla b: ABT 1700 Bolaños, Jalisco, Mexico
Antonio de Bobadilla b: ABT 1702
Maria Leonarda de Bobadilla b: ABT 1705

Much documentation has been done on Bobadilla from Tlaltenango from late 1500's to mid 1600's, and I wanted to know if they were related in any way.

One last thing, I found a "Defuncion Record" in Colotlan from 08/26/1736 for Antonio de Bobadilla from Cartagenas and was married to Maria Juana de Villa. Could this be the same person (Antonio de Bobadilla), and they perhaps mispelled wife's last name during this time of chaos when people were dying daily of Tabardillo.

https://familysearch.org/pal:/MM9.3.1/TH-1-18455-14181-36?cc=1874591&wc=3JHQ-ZN5:171936201,171936202,172897101

Thanks
Ruben Rojas Delgado