Possible new siblings of Lope Ruiz de Esparza

Carlos de Esparza & Rafael de Esparza

Carlos arrived in Ecuador in 1582

Rafael arrived in Mexico City in 1578 (before Lope!)

I have no doubt there related somehow, they descend from the same House of Esparza.
There might be a higher chance that Rafael is the brother of Lope. Since they both arrived in Mexico city.

Source:

Daniel Mendez del Camino